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MK-7 Reduces Joint Inflammation of Rheumatoid Arthritis

MK-7 Reduces Joint Inflammation of Rheumatoid Arthritis

In normal joints, the synovium is a thin, delicate lining that provides nutrients for cartilage. Synovial cells make joint lubricants, collagen, and fibronectin for structural joint support. In rheumatoid arthritis (RA), this lining thickens and inflames.

MK-7 is one of the menaquinones, which doctors believe kill RA synovial cells. A recent study found MK-4 beneficial in RA, but MK-7 is more bioavailable, hence this study.
In the study, 84 men and women with RA took 100 mcg of MK-7 per day, or a placebo, while continuing on other medications. After three months, while the placebo group had not changed, those taking MK-7 had measurably lower levels of two types of inflammation, fewer of the proteins that degrade connective tissue in RA, and lower disease activity scores in 28 joints.

Reference: European Journal of Pharmacology; August, 2015, Published Online


Additional Comments from Don Goldberg

MK-7 is a  bioactive form of vitamin K2 found naturally occurring in Natto. There are three forms of vitamin K: vitamin K1 (phylloquinone), found in plants, vitamin K2 (menaquinone), produced by bacteria (in your intestines and elsewhere), and vitamin K3 (menadione), a synthetic form. MK-7 is ten times better absorbed than vitamin K1 from spinach. Vitamin K is essential to bone health and proper blood clotting.

The K2 form is preferred in supplements because it is better absorbed, has higher activitys and a longer half-life.

MK-7 is the form of vitamin K2 used in supplements. According to Jarrow Formulas, their MK-7 is made via fermentation by Bacillus subtilus natto.  MK-7 (Menaquinone-7) is the bioactive form of vitamin K2 found naturally occurring in Natto.

If you are currently taking blood thinning medications, talk to the pharmacists or nutritionists at Willner Chemists for guidance.
Note: A version of this article appeared in the Summer 2016 Willner Window Newsletter/Product Catalog.

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